Power to help reverse an opioid overdose
- Concentrated 4 mg dose
- Needle-free and designed for ease-of-use*
- Broad access and affordability†
Not a substitute for emergency medical care. Repeated doses may be necessary.
Please see Indications and Important Safety Information
*Administer in accordance with the Instructions for Use.
†Based on data from IMS Health and MMIT Formulary Analytics.
Real Stories from Real People
Family members, friends and caregivers share how their lives have been impacted by an opioid overdose.
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Fast. Strong. Proven.
WHAT IS
NARCAN® NASAL SPRAY
NARCAN® (naloxone HCl) Nasal Spray is the first and only FDA-approved nasal form of naloxone for the emergency treatment of a known or suspected opioid overdose.
NARCAN® Nasal Spray counteracts the life-threatening effects of opioid overdose. Since most accidental overdoses occur in a home setting, it was developed for first responders, as well as family, friends, and caregivers.
Administer in accordance with the Instructions for Use. Repeated doses may be necessary. NARCAN® Nasal Spray is not a substitute for emergency medical care. Always get help immediately, even if the person wakes up because they may relapse into respiratory depression. The use of NARCAN® may result in symptoms of acute opioid withdrawal.
Please see Indications and Important Safety Information on this page in the use of this product.
See how it works
Watch this brief video to learn more about the dangers posed by opioids and how NARCAN® Nasal Spray can reverse their effects in the event of an overdose.
HISTORY OF
NARCAN® NASAL SPRAY 4mg Download PDF
Who is at Risk?
Anyone exposed to prescription or illegal opioids should be aware of risk factors that may lead to an accidental, life-threatening or deadly opioid overdose.
People at higher risk of an opioid overdose include: anyone who takes prescription opioids (such as Percocet® or OxyContin®), especially those taking higher doses, or taking them in combination with other substances such as alcohol or sleep medications known as benzodiazepines (which include Ativan®, Xanax®, and Valium®). Additionally, risk is increased for those with medical conditions such as depression or lung/liver disease and anyone who injects opioids, such as heroin or fentanyl.
People who may be at a higher risk include: anyone who has a reduced tolerance of opioids following detoxification, anyone with a suspected or confirmed history of substance abuse, dependence, or non-medical use of prescription or illegal drugs.
NARCAN® (naloxone HCI) NASAL SPRAY CAN BE OBTAINED AT VARIOUS LOCAL RETAIL PHARMACIES ACROSS THE COUNTRY
Remember to ask for the first and only FDA approved take-home intranasal device, NARCAN® Nasal Spray 4 mg.
If you or someone you care for has opioids at home, you can obtain NARCAN® Nasal Spray from your local pharmacy. There are many
states where NARCAN® Nasal Spray is available without a prescription from your physician.
To see if your state is one of them, click here.
For Patients, Family, Caregivers:
ADAPT Pharma is committed to making NARCAN® Nasal Spray affordable and accessible to everyone. ADAPT has entered into collaborations with wholesalers, distributors, and retail pharmacies to ensure broad-based availability. ADAPT has also entered into agreements with major Pharmacy Benefits Managers and insurance companies (including Medicaid) to make sure the cost to the patient is reasonable and affordable. In fact, 97% of insured lives in the U.S. have coverage for NARCAN® Nasal Spray.*
If you are a patient or caregiver and would like to find out how to obtain NARCAN® Nasal Spray, enter your zip code here.
That zip code was not found.
Please enter a zip code to find pharmacies nearby.
See the list below for pharmacies near you. Call ahead to ensure they have NARCAN® Nasal Spray in stock.
NOTE: NARCAN® Nasal Spray is a prescription product. However, a number of states do not require a physician’s prescription to obtain NARCAN® Nasal Spray. In these states, pharmacists can provide an individualized prescription directly to residents. This is called “direct dispensing”.
See the list below for pharmacies near you. Call ahead to ensure they have NARCAN® Nasal Spray in stock.
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* MMIT Formulary Analytics, July 2018
For Direct Purchasers:
If you are a first responder (EMS, Fire Department, Police, or community organization) and would like to make a bulk purchase, click here.
HOW TO USE
NARCAN® NASAL SPRAY
In opioid overdose emergencies, recognizing symptoms and taking prompt action is critical to potentially saving a life. If you suspect an opioid overdose, administer NARCAN® Nasal Spray and get emergency medical assistance right away.
Key Steps to Administering NARCAN® Nasal Spray:
-
Peel
Peel back the package to remove the device. Hold the device with your thumb on the bottom of the plunger and 2 fingers on the nozzle.
-
Place
Place and hold the tip of the nozzle in either nostril until your fingers touch the bottom of the patient’s nose.
-
Press
Press the plunger firmly to release the dose into the patient’s nose.
Administer in accordance with the Instructions for Use. Please refer to the Quick Start Guide
Not a Substitute for Emergency Medical Care. When administering NARCAN® Nasal Spray, always be sure to call 911 right away, even if the person wakes up. Keep the patient under surveillance or close watch. If breathing does not return to normal or if breathing difficulty resumes, after 2-3 minutes, give an additional dose of NARCAN® Nasal Spray using a new device in the alternate nostril.
Please see additional safety considerations below.
SEE HOW TO USE
NARCAN® NASAL SPRAY
In this video, you'll learn:
- How to recognize symptoms of an opioid overdose
- How to administer NARCAN® Nasal Spray
- How to proceed if the person regains consciousness before help arrives
PHARMACY
TRAINING VIDEO
In this training module, you'll learn:
- How to identify and speak with at-risk patients
- Best practices for educating patients and caregivers on opioid safety and the role of naloxone
- NARCAN® Nasal Spray access and affordability
Law enforcement
Roll call video
In this training module, you'll learn:
- How to identify an opioid overdose and check for response
- Proper administration of NARCAN® Nasal Spray
- How to place the patient in the recovery position until emergency medical assistance arrives
Additional Resources
Download the
INDICATIONS AND IMPORTANT SAFETY INFORMATION
What is NARCAN® (naloxone HCl) Nasal Spray?
NARCAN® Nasal Spray is a prescription medicine used for the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.
NARCAN® Nasal Spray is to be given right away and does not take the place of emergency medical care. Get emergency medical help right away after giving the first dose of NARCAN® Nasal Spray, even if the person wakes up.
NARCAN® Nasal Spray is safe and effective in children for known or suspected opioid overdose.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about NARCAN® Nasal Spray?
NARCAN® Nasal Spray is used to temporarily reverse the effects of opioid medicines. The medicine in NARCAN® Nasal Spray has no effect in people who are not taking opioid medicines. Always carry NARCAN® Nasal Spray with you in case of an opioid emergency.
- Use NARCAN® Nasal Spray right away if you or your caregiver think signs or symptoms of an opioid emergency are present, even if you are not sure, because an opioid emergency can cause severe injury or death. Signs and symptoms of an opioid emergency may include:
- unusual sleepiness and you are not able to awaken the person with a loud voice or by rubbing firmly on the middle of their chest (sternum)
- breathing problems including slow or shallow breathing in someone difficult to awaken or who looks like they are not breathing
- the black circle in the center of the colored part of the eye (pupil) is very small, sometimes called "pinpoint pupils" in someone difficult to awaken
- Family members, caregivers, or other people who may have to use NARCAN® Nasal Spray in an opioid emergency should know where NARCAN® Nasal Spray is stored and how to give NARCAN® Nasal Spray before an opioid emergency happens.
- Get emergency medical help right away after giving the first dose of NARCAN® Nasal Spray. Rescue breathing or CPR (cardiopulmonary resuscitation) may be given while waiting for emergency medical help.
- The signs and symptoms of an opioid emergency can return after NARCAN® Nasal Spray is given. If this happens, give another dose after 2 to 3 minutes using a new NARCAN® Nasal Spray and closely watch the person until emergency help is received.
Who should not use NARCAN® Nasal Spray?
Do not use NARCAN® Nasal Spray if you are allergic to naloxone hydrochloride or any of the ingredients in NARCAN® Nasal Spray.
What should I tell my healthcare provider before using NARCAN® Nasal Spray?
Before using NARCAN® Nasal Spray, tell your healthcare provider about all of your medical conditions, including if you:
- have heart problems
- are pregnant or plan to become pregnant. Use of NARCAN® Nasal Spray may cause withdrawal symptoms in your unborn baby. Your unborn baby should be examined by a healthcare provider right away after you use NARCAN® Nasal Spray.
- are breastfeeding or plan to breastfeed. It is not known if NARCAN® Nasal Spray passes into your breast milk.
Tell your healthcare provider about the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of NARCAN® Nasal Spray?
NARCAN® Nasal Spray may cause serious side effects, including:
Sudden opioid withdrawal symptoms. In someone who has been using opioids regularly, opioid withdrawal symptoms can happen suddenly after receiving NARCAN® Nasal Spray and may include:
- body aches
- diarrhea
- increased heart rate
- fever
- runny nose
- sneezing
- goose bumps
- sweating
- yawning
- nausea or vomiting
- nervousness
- restlessness or irritability
- shivering or trembling
- stomach cramping
- weakness
- increased blood pressure
In infants under 4-weeks old who have been receiving opioids regularly, sudden opioid withdrawal may be life-threatening if not treated the right way. Signs and symptoms include: seizures, crying more than usual, and increased reflexes.
These are not all of the possible side effects of NARCAN® Nasal Spray. Call your doctor for medical advice about side effects. You may report side effects to the FDA at
Please see full Prescribing Information, including the Patient Information, for NARCAN® Nasal Spray.